Useful Genetics
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Module 1 1 - Begin with the Basics
DNA, genes, and how they make each of us (and also dogs!) unique.
Unit 1 Useful Genetics Overview
Unit 2 Module 1 Overview: How different are we?
Unit 3 > How different are we? (Lecture 1A)
Unit 4 Properties of DNA (Lecture 1B)
Unit 5 Properties of Genes (Lecture 1C)
Unit 6 Why molecular biology is confusing (Lecture 1D)
Unit 7 Properties of Chromosomes (Lecture 1E)
Unit 8 Life cycles and ploidy (Lecture 1F)
Unit 9 Comparing DNA sequences (Lecture 1G)
Unit 10 Genetic & Evolutionary Relationships of Human Populations (Lecture 1H)
Module 2 2
2
Unit 1 Module 2 Overview: Mutations
Unit 2 Fidelity of DNA replication (Lecture 2A)
Unit 3 Why most mutations are harmless (Lecture 2B)
Unit 4 Types of Mutations And Their Consequences (Lecture 2C)
Unit 5 Germline and Somatic Mutations (Lecture 2D)
Unit 6 Mutagens (what should we worry about) (Lecture 2E)
Unit 7 Mutations, Selection, & Evolvability (Lecture 2F)
Unit 8 Origins and Evolution of New Genes & Gene Families (Lecture 2G)
Unit 9 Comparing DNA Sequences Reveals Evolutionary Relationships (Lecture 2H)
Module 3 3
3
Unit 1 Module 3 Overview: DNA differences & gene functions
Unit 2 Protein Basics (Lecture 3A)
Unit 3 Catalytic Proteins (Lecture 3B)
Unit 4 Structural, transport and carrier proteins (Lecture 3C)
Unit 5 Regulatory Proteins and RNAs (Lecture 3D)
Unit 6 Homozygous Phenotypes (Lecture 3E)
Unit 7 Diploids: Heterozygous Phenotypes (Lecture 3F)
Unit 8 All About Dominance (Lecture 3G)
Unit 9 How genes are named (Lecture 3H)
Unit 10 Gene interaction in biochemical pathways (Lecture 3I)
Unit 11 Regulatory interactions (Lecture 3J)
Unit 12 How somatic mutations cause cancer (Lecture 3K)
Module 4 4
4
Unit 1 Module 4 Overview: Natural genetic variation
Unit 2 Sex Chromosomes & Sex Determination (Lecture 4A)
Unit 3 Expression of X-linked Genes in Females (Lecture 4B)
Unit 4 Expression of X-linked genes in males (Lecture 4C)
Unit 5 Can Genetic Variation Explain Phenotypic Variation? (Lecture 4D)
Unit 6 Most Natural Variation Has Very Small Effects (Lecture 4E)
Unit 7 Many Natural Genetic Variants Affect Multiple Traits (Lecture 4F)
Unit 8 Effects of natural genetic variation depend on the environment (Lecture 4G)
Unit 9 Effects of natural genetic variation depend on chance (Lecture 4H)
Unit 10 How natural Genetic Variation Affects the Risk of Cancer (Lecture 4I)
Module 5 5
5
Unit 1 Module 5 Overview: Personal genomics
Unit 2 DNA Fingerprinting (Lecture 5A)
Unit 3 Analyzing a single gene or gene "panel" (Lecture 5B)
Unit 4 SNP-typing the genome (Lecture 5C)
Unit 5 SNP-typing the genome, part 1 (Lecture 5D)
Unit 6 SNP-typing services (Lecture 5E)
Unit 7 Exome sequencing (Lecture 5F)
Unit 8 Haplotypes (Lecture 5G)
Unit 9 Ancestry (Lecture 5H)
Unit 10 Ethical and social issues surrounding personal genomics (Lecture 5I)
Unit 11 Not-so-personal genomics (Lecture 5J)
Module 6 6
6
Unit 1 Module 6 Overview: The mechanics of inheritance
Unit 2 Mitosis (Lecture 6A)
Unit 3 Sexual life cycles (Lecture 6B)
Unit 4 Meiosis, the basics (Lecture 6C)
Unit 5 Following genotypes through meiosis, part 1 (Lecture 6D)
Unit 6 More about meiosis: homolog pairing and crossing over (Lecture 6E)
Unit 7 Following genotypes through meiosis (this time with crossovers) (Lecture 6F)
Unit 8 Mating (Lecture 6G)
Unit 9 Following Alleles Through Generations (Lecture 6H)
Unit 10 Relatedness (Lecture 6I)
Unit 11 Sex chromosomes in meiosis (Lecture 6J)
Module 7 7
7
Unit 1 Module 7 Overview: Genetic analysis
Unit 2 Genetic Analysis Began With Mendel (Lecture 7A)
Unit 3 Mendel's Findings & What We Now Know (Lecture 7B)
Unit 4 How to do Genetic Analysis (Lecture 7C)
Unit 5 Mendel's Genetic Analysis (Lecture 7D)
Unit 6 Detecting Sex-Linkage, Predicting Outcomes (Lecture 7E)
Unit 7 Using Crosses To Investigate Locations of Autosomal Genes (Lecture 7F)
Unit 8 Using Crosses to Investigate Gene Function (Lecture 7G)
Unit 9 Using pedigrees to investigate family inheritance (Lecture 7H)
Unit 10 Genetic Analysis: Numbers Matter (Lecture 7I)
Module 8 8
8
Unit 1 Module 8: All About Breeding & Inbreeding
Unit 2 Heritability (Lecture 8A)
Unit 3 GWAS Redux (Lecture 8B)
Unit 4 Inbreeding (Lecture 8C)
Unit 5 Inbreeding in livestock and pets (Lecture 8D)
Unit 6 Inbreeding and genetic variation in evolution and conservation (Lecture 8E)
Unit 7 Hybrids (Lecture 8F)
Unit 8 Plant breeding and transgenics (Lecture 8G)
Module 9 Chromosomal Changes
Chromosomal Changes
Unit 1 Module 9 Overview: Chromosomal changes
Unit 2 Polyploidy (Lecture 9A)
Unit 3 Aneuploidy (Lecture 9B)
Unit 4 Aneuploidy for sex chromosomes (Lecture 9C)
Unit 5 Chromosome rearrangements (Lecture 9D)
Unit 6 Consequences of chromosome rearrangements (Lecture 9E)
Unit 7 Small changes (structural variation) (Lecture 9F)
Unit 8 Junk and selfish DNA (Lecture 9G)
Unit 9 Genome evolution (Lecture 9H)
Module 10 10
10
Unit 1 Module 10: Intro to Advanced Topics
Unit 2 Origin of Life (Lecture 10A)
Unit 3 Mitochondrial Genetics (Lecture 10B)
Unit 4 Epigenetics (Lecture 10C)
Unit 5 Mosaics & Chimeras (Lecture 10D)
Unit 6 Fetal DNA Gets Around (Lecture 10E)
Unit 7 Genetics of Aging (Lecture 10F)